Developmental and Neurobehavioral Toxicity of Tetrabromobisphenol A Mono(2-hydroxyethyl) Ether (TBBPA-MHEE) in Zebrafish Larvae: Oxidative/Inflammatory Responses and Candidate ErbB-Related Signaling.

Yuhan Deng, Yuqi Zhao, Jiujiu Cao, Tianyu Chen, Ziyu Jiang, Yamin Zhang, Jiannan Chen

Abstract read

In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuhan DengCollege of Food and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China.

Yuqi ZhaoCollege of Life Sciences, Nanjing Normal University, Nanjing 210023, China.

Jiujiu CaoCollege of Life Sciences, Nanjing Normal University, Nanjing 210023, China.

Tianyu ChenCollege of Life Sciences, Nanjing Normal University, Nanjing 210023, China.

Ziyu JiangCollege of Life Sciences, Nanjing Normal University, Nanjing 210023, China.

Yamin ZhangCollege of Life Sciences, Nanjing Normal University, Nanjing 210023, China.

Jiannan ChenCollege of Life Sciences, Nanjing Normal University, Nanjing 210023, China.ORCID 0000-0003-4903-022X

Funding

National Natural Science Foundation of China 82373183

6 · The paper itself

Abstract

Tetrabromobisphenol A mono(2-hydroxyethyl) ether (TBBPA-MHEE) is an important byproduct during the production of tetrabromobisphenol A (TBBPA) and its related derivatives. Although it has been detected in aquatic environments, its in vivo developmental toxicity and underlying mechanisms remain poorly understood. In this study, zebrafish were used as a model organism to evaluate the early developmental toxicity, neurobehavioral toxicity, and candidate molecular responses associated with TBBPA-MHEE. The 96 h median lethal concentration (96 h-LC

Indexed as

ErbB signaling pathwayneurodevelopmental toxicityoxidative stressPI3K/Akt/mTOR axistetrabromobisphenol A mono(2-hydroxyethyl) ether (TBBPA-MHEE)zebrafish

Identifiers

PMID42510668

DOI10.3390/biology15141120

PMCPMC13403645

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.