Evidence map›Paper›PMID 42510689›Full record

ReviewBiology2026

Hyperlipidemia Intervention from Medicine-Food Homologous Plants: A Review of Regulatory Status, Processing Techniques, and Lipid-Lowering Mechanisms.

Jian Chen, Daomin Liu, Peifeng Zhu, Lu Liu

Abstract readReview
In one paragraph

Review in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jian ChenYunnan Yunzhong Institute of Nutrition and Health, College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Daomin LiuYunnan Yunzhong Institute of Nutrition and Health, College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Peifeng ZhuYunnan Yunzhong Institute of Nutrition and Health, College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Lu LiuYunnan Yunzhong Institute of Nutrition and Health, College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.ORCID 0000-0001-5101-5067

Funding

the Key Laboratory of Yunnan Provincial Department of Education on Substance Benchmark Research of Ethnic Medicines 2022YGZ02the Major Science and Technology Special Project from Yunnan Provincial Science and Technology Department 202202A100009,202302A310006
6 · The paper itself

Abstract

backgroundThe rising global prevalence of hyperlipidemia is closely linked to current dietary patterns, sparking interest in "medicine-food homology" (MFH) plants as natural resources that provide both nutritional benefits and therapeutic effects. This study reviews MFH plants used to treat hyperlipidemia, incorporating changes in regulatory mechanisms, the impact of processing on bioavailability, and evidence of their lipid-lowering effects.

methodsThis narrative review, supported by a structured literature search, summarizes the practical applications of MFH plant species with both medicinal and edible properties and discusses their bioactive components and lipid-regulating mechanisms.

resultsMFH plants not only contain anti-lipid active ingredients but also have improved bioavailability after processing through processing technology and function through lipid metabolism pathways and the gut-liver axis.

conclusionsThe development and application of MFH plants face several challenges, including incomplete and inconsistent international regulatory frameworks, difficulties in quality control, and limited clinical evidence for lipid-lowering mechanisms. Nevertheless, MFH plants hold promise for development into functional foods or nutraceuticals aimed at supporting lipid regulation.

Indexed as

anti-hyperlipidemiabioactive componentsmedicine-food homology

Identifiers

PMID42510689
PMCPMC13403650

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.