Evidence map›Paper›PMID 42510944›Full record

ReviewCurrent issues in molecular biology2026

Artificial Intelligence-Enabled Exosomes in Precision Oncology: A Framework for Clinical Utility and Biomedical Applications.

Prakash Gangadaran, Ramya Lakshmi Rajendran, Muthu Subash Kavitha, Byeong-Cheol Ahn

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Prakash GangadaranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea.ORCID 0000-0002-0658-4604
Ramya Lakshmi RajendranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea.ORCID 0000-0001-6987-0854
Muthu Subash KavithaSchool of Information and Data Sciences, Nagasaki University, Nagasaki 852-8521, Japan.ORCID 0000-0002-1676-561X
Byeong-Cheol AhnDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea.ORCID 0000-0001-7700-3929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are 30-150 nm extracellular vesicles that convey molecular information reflecting the physiological and pathological states of their source cells. In precision oncology, they function as a non-invasive "liquid biopsy," enabling real-time monitoring of tumor dynamics and metastasis. However, extreme biofluid heterogeneity poses significant challenges for their isolation and analysis using conventional statistical approaches. This review aims to examine how artificial intelligence (AI), specifically machine learning and deep learning, transforms complex exosomal "noise" into actionable clinical insights. AI enhances exosome isolation, enables disease-specific biomarker identification, and predicts therapeutic responses with high precision. Integrating multi-omics data and single-exosome analysis enables AI-driven models to facilitate early cancer detection and therapeutic resistance monitoring. Despite challenges related to standardization and data privacy, the convergence of AI and exosome biology is poised to transform reactive cancer treatments into a proactive, personalized medical ecosystem. This approach also provides a framework for managing other complex systemic diseases.

Indexed as

artificial intelligencebiomarkersexosomesliquid biopsyprecision oncology

Identifiers

PMID42510944
PMCPMC13406987

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.