Evidence map›Paper›PMID 42511537›Full record

ArticleInternational journal of molecular sciences2026

Integrated Immunohistochemical and Ultrastructural Characterization of Layer-Specific Capillary Specialization in the Human Vocal Fold.

Roxana-Andreea Popa, Cosmin-Gabriel Popa, Delia Hînganu, Fabian Cezar Lupu, Cristinel Ionel Stan, Marius Valeriu Hînganu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roxana-Andreea PopaDepartment of Morpho-Functional Sciences I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Cosmin-Gabriel PopaDepartment of Morpho-Functional Sciences I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-7124-3179
Delia HînganuDepartment of Morpho-Functional Sciences I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-9856-6496
Fabian Cezar LupuDepartment of Mechanical, Mechatronics and Robotics Engineering, Mechanical Engineering Faculty, "Gheorghe Asachi" Technical University of Iasi, 700050 Iasi, Romania.ORCID 0009-0009-6872-8616
Cristinel Ionel StanDepartment of Morpho-Functional Sciences I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Marius Valeriu HînganuDepartment of Morpho-Functional Sciences I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.

Funding

Health Programme (PS) 2021-2027, Policy Objective 4, Priority 3 351058
6 · The paper itself

Abstract

The human true vocal fold exhibits a complex microvascular organization essential for its biomechanical and metabolic function. This study aimed to quantitatively assess CD31/PECAM-1-positive microvascular structures across the superficial lamina propria (SLP), deep lamina propria (DLP), and vocalis muscle (MV), and to integrate these findings with neuron-specific enolase (NSE) and scanning electron microscopy (SEM) observations. A retrospective analysis was performed on 21 formalin-fixed specimens. CD31 immunohistochemistry was used for endothelial identification, NSE immunohistochemistry was applied for the evaluation of neural elements, while SEM provided complementary ultrastructural information on extracellular matrix organization. Total microvascular density differed significantly among layers (χ

Indexed as

CapillariesVocal CordsAdultAgedFemaleHumansImmunohistochemistryMaleMicroscopy, Electron, ScanningMiddle AgedMucous MembranePhosphopyruvate HydratasePlatelet Endothelial Cell Adhesion Molecule-1Retrospective StudiesPECAM1 protein, humanPhosphopyruvate HydratasePlatelet Endothelial Cell Adhesion Molecule-1CD31extracellular matrixmicrovascular densityneurovascular microenvironmentNSESEMtrue vocal fold

Identifiers

PMID42511537
PMCPMC13411090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.