Evidence map›Paper›PMID 42511608›Full record

ArticleInternational journal of molecular sciences2026

Interleukin-2-Mediated Engraftment of Human Peripheral Blood Mononuclear Cells in Immunodeficient Mice to Develop a Model of HIV Infection: New Criteria for Engraftment Monitoring.

Aleksey M Nagornykh, Marina A Tyumentseva, Aleksandr I Tyumentsev, Leonid A Fedotov, Konstantin S Karbyshev, Lubov S Danilova, Andrey S Akinin, Vasiliy G Akimkin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aleksey M NagornykhCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.ORCID 0000-0002-8320-2999
Marina A TyumentsevaCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.ORCID 0000-0002-3145-3702
Aleksandr I TyumentsevCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.ORCID 0000-0003-0537-2586
Leonid A FedotovCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.
Konstantin S KarbyshevCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.ORCID 0000-0002-8992-4861
Lubov S DanilovaCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.
Andrey S AkininCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.ORCID 0009-0007-4256-0435
Vasiliy G AkimkinCentral Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Moscow 111123, Russia.ORCID 0000-0003-4228-9044

Funding

Ministry of Science and Higher Education of the Russian Federation Creation and development of the «World-class Genomic Research Center for Ensuring Biological Safety and Technological Independence under the Federal Scientific and Technical Program for the Development of Genetic Technologies», agreement № 075-15-2025-517
6 · The paper itself

Abstract

Graft failure and graft-versus-host disease are the main limiting factors for the engraftment of not only xenogeneic but also allogeneic grafts. Long-term engraftment of human immune cells in mice with severe combined immunodeficiency and

Indexed as

HIV InfectionsInterleukin-2Leukocytes, MononuclearAnimalsDisease Models, AnimalFemaleGraft vs Host DiseaseHumansMaleMiceMice, SCIDInterleukin-2graft-versus-host diseasehuman immunodeficiency virusimmune-inflammation indicesperipheral blood mononuclear cellsT-helper cells

Identifiers

PMID42511608
PMCPMC13409855

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.