ArticleInternational journal of molecular sciences2026
Salvianolic Acid A Induces Ferroptosis in Non-Small Cell Lung Cancer via the SRC/YAP/GPX4 Axis.
Ruyu Jiang, Haoshu Liu, Hairong Xiang, Xiaomeng Tang, Linfeng Zhao, Dawei Zeng, Yue Zhang, Jiazhen Xie, Yanju Gong, Lan Yang
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Ruyu JiangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID 0009-0004-8236-7048 Haoshu LiuCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Hairong XiangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID 0009-0007-5753-941X Xiaomeng TangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Linfeng ZhaoCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Dawei ZengCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yue ZhangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jiazhen XieCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yanju GongCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Lan YangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Funding
Chengdu University of Traditional Chinese Medicine XCZX2022001Science and Technology Department of Sichuan Province 2024NSFSC0705
6 · The paper itselfAbstract
Lung cancer is the most common malignant tumor worldwide in terms of both incidence and mortality, and the development of highly effective, low-toxicity therapeutic strategies remains an urgent clinical challenge. Here, we report that Salvianolic acid A (SAA), a natural compound extracted from
Indexed as
Caffeic AcidsCarcinoma, Non-Small-Cell LungFerroptosisLactatesLung NeoplasmsPhospholipid Hydroperoxide Glutathione Peroxidasesrc-Family KinasesTranscription FactorsAnimalsCell Line, TumorCell ProliferationHumansMiceReactive Oxygen SpeciesSignal TransductionYAP-Signaling ProteinsCaffeic AcidsLactatesPhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen Speciessalvianolic acid Asrc-Family KinasesTranscription FactorsYAP1 protein, humanYAP-Signaling ProteinsferroptosisGPX4non-small cell lung cancerSalvianolic acid ASRCYAP
Identifiers
PMID42511609
PMCPMC13410247
What Socratic holds
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