ReviewInternational journal of molecular sciences2026
Host-Pathogen Interaction as a Driver of Cellular Senescence: Microbial Triggers and Host Response.
Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Despite extensive research, the complex relationship between cellular senescence, aging, and host-pathogen interactions remains incompletely understood. This paper aims to review cellular and molecular alterations of senescent cells and critically examine the role of bacterial infections as key drivers in immunosenescence. Molecular mechanisms underlying pathogen-induced stress responses and the subsequent impact on host tissues and immune function are also highlighted. The novelty of this work lies in integrating current knowledge into direct and indirect mechanisms by which bacterial pathogens induce senescence, including genotoxic effects, oxidative stress, and disruption of host signaling pathways. Particular emphasis is placed on how bacterial virulence factors modulate critical pathways such as p53-p21, p16
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.