Evidence map›Paper›PMID 42512404›Full record

ReviewCancers2026

Muscle-Tumor Crosstalk in Exercise Oncology: Exercise-Induced Myokines and Cancer Cachexia.

Amirhossein Ahmadi Hekmatikar, Francesco Bettariga, Álvaro López Llorente, Diego Fernández-Lázaro, Katsuhiko Suzuki, D Maryama Awang Daud

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amirhossein Ahmadi HekmatikarDepartment of Physical Education and Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran 10600, Iran.ORCID 0009-0001-3331-8272
Francesco BettarigaSchool of Human Performance, Rehabilitation and Population Health, INSIGHT Research Institute, University of Technology Sydney, Sydney, NSW 2021, Australia.ORCID 0000-0002-4977-5494
Álvaro López LlorenteDepartment of Sports Medicine, Burgos Burpellet BH UCI Pro Team, 09007 Burgos, Spain.ORCID 0009-0006-6565-9270
Diego Fernández-LázaroNeurobiology Research Group, Faculty of Medicine, University of Valladolid, 47005 Valladolid, Spain.ORCID 0000-0002-6522-8896
Katsuhiko SuzukiFaculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.ORCID 0000-0002-6572-5809
D Maryama Awang DaudHealth Through Exercise and Active Living (HEAL) Research Unit, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu 88400, Sabah, Malaysia.ORCID 0000-0001-9605-9522

Funding

European Regional Development Fund (FEDER) 067/230003Junta of Castile and León 067/230003
6 · The paper itself

Abstract

Exercise-induced myokines, such as IL-6, irisin, and myostatin, play crucial roles in mediating systemic adaptations and modulating tumor progression. This narrative review synthesizes evidence on how regular moderate-intensity exercise affects the myokine network within the tumor microenvironment (TME) of solid tumors. Results from the 86 included studies indicate that structured training (aerobic: 45-65% VO

Indexed as

cancerexerciseexerkinesmyokinessolid tumors

Identifiers

PMID42512404
PMCPMC13407122

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.