SynthesisMedicina (Kaunas, Lithuania)2026
Diagnostic Accuracy of p16 Immunohistochemistry as a Marker of High-Risk HPV in Invasive Laryngeal Squamous Cell Carcinoma: A Systematic Review.
Ana-Maria Stanoiu, Delia Hutanu, Maria Sorop-Florea, Alexandru Alexandru, Norberth-Istvan Varga, Iulia Cristina Bagiu, Mihaela-Diana Popa, Bogdan Hirtie, Nicolae-Constantin Balica, Cristian-Ion Mot and 1 more
Abstract readSystematic Review
In one paragraphSynthesis in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Ana-Maria StanoiuDoctoral School, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.
Delia HutanuDepartment Biology-Chemistry, Faculty of Chemistry-Biology-Geography, West University of Timisoara, Pestalozzi, 16, 300315 Timisoara, Romania.ORCID 0000-0002-1335-6845 Maria Sorop-FloreaFaculty of Medical and Behavioral Sciences, "Constantin Brancusi" University, Tineretului Street, No. 4, 210185 Targu Jiu, Romania.
Alexandru AlexandruDoctoral School, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0009-0005-2245-231X Norberth-Istvan VargaDepartment of Nursing, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0009-0002-0320-6904 Iulia Cristina BagiuDepartment of Microbiology, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0000-0003-3099-8249 Mihaela-Diana PopaDepartment of Microbiology, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0009-0008-7487-4639 Bogdan HirtieDepartment of Ear Nose Throat, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.
Nicolae-Constantin BalicaDepartment of Ear Nose Throat, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0000-0001-7755-4608 Cristian-Ion MotDepartment of Ear Nose Throat, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.
Ioana-Delia HorhatDepartment of Ear Nose Throat, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania.ORCID 0000-0001-7210-1263 Funding
Victor Babeș University of Medicine and Pharmacy Timișoara
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
Carcinoma, Squamous CellCyclin-Dependent Kinase Inhibitor p16ImmunohistochemistryLaryngeal NeoplasmsPapillomavirus InfectionsBiomarkers, TumorHuman Papillomavirus VirusesHumansReproducibility of ResultsBiomarkers, TumorCyclin-Dependent Kinase Inhibitor p16diagnostic accuracyhigh-risk HPVHPV-driven carcinogenesishuman papillomaviruslaryngeal cancerlaryngeal squamous cell carcinomap16 immunohistochemistryRNA in situ hybridizationsurrogate marker
Identifiers
PMID42512914
PMCPMC13414022
What Socratic holds
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LicenceCC BY
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