ReviewMolecules (Basel, Switzerland)2026
Recent Advances in Molecularly Imprinted Membranes: Structure-Activity Relationships, Morphology Control, and Separation Applications.
Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Molecularly imprinted membranes (MIMs) have demonstrated tremendous potential in the field of high-efficiency separation due to their specific molecular recognition capabilities. This review aims to elucidate the underlying mechanisms governing MIMs' performance and, moving beyond traditional classification frameworks, systematically reconstructs the classification system for MIMs from the perspectives of the spatial distribution of imprinted sites, the chemical topology of the matrix, and mass transfer kinetics. The article focuses on the decisive influence of key physical parameters such as pore size, specific surface area, hydrophilicity/hydrophobicity, and swellability on separation efficiency. It provides an in-depth analysis of the spatial matching between pore size and target molecules, the nonlinear relationship between specific surface area and adsorption capacity, and the mechanisms by which mechanical strength and swelling behavior constrain the long-term stability of the membranes. Addressing the common bottlenecks faced by MIMs "high mass transfer resistance and poor accessibility of recognition sites" this paper critically summarizes cutting-edge morphological optimization strategies, such as multi-level pore construction, nanocomposite reinforcement, and surface topological engineering, aiming to elucidate how microstructural regulation can achieve a synergistic enhancement of both high throughput and high selectivity. Finally, by reviewing breakthroughs in MIMs applications for biomedical extraction and environmental pollutant remediation, this review not only clarifies the principles governing material suitability across different scenarios but also provides a systematic technical reference for the development of next-generation, high-performance, industrial-scale MIMs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.