Evidence map›Paper›PMID 42513956›Full record

ArticleMicroorganisms2026

Diagnosis of Respiratory Infections Using Syndromic Panels: A Ct-Based Approach Beyond Qualitative Detection.

Maria Antonella Zingaropoli, Gianluca Bruno Tassone, Eleonora Coratti, Donatella Maria Rodio, Martina Bernassola, Roberta Campagna, Lucilla Caivano, Francesca Pulcinelli, Fabio Midulla, Gioacchino Galardo and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maria Antonella ZingaropoliMicrobiology and Virology Unit, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-9479-8559
Gianluca Bruno TassoneDepartment of Molecular Medicine, Sapienza University of Rome, 00141 Rome, Italy.
Eleonora CorattiDepartment of Molecular Medicine, Sapienza University of Rome, 00141 Rome, Italy.
Donatella Maria RodioMicrobiology and Virology Unit, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Martina BernassolaMicrobiology and Virology Unit, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Roberta CampagnaDepartment of Molecular Medicine, Sapienza University of Rome, 00141 Rome, Italy.ORCID 0000-0002-7381-9071
Lucilla CaivanoDepartment of Molecular Medicine, Sapienza University of Rome, 00141 Rome, Italy.
Francesca PulcinelliDepartment of Pediatrics and Infantile Neuropsychiatry, Sapienza University of Rome, 00141 Rome, Italy.
Fabio MidullaDepartment of Pediatrics and Infantile Neuropsychiatry, Sapienza University of Rome, 00141 Rome, Italy.
Gioacchino GalardoDepartment of Medical and Cardiovascular Sciences, Sapienza University of Rome, 00141 Rome, Italy.
Alessandra PierangeliDepartment of Well-being, Health and Environmental Sustainability (BeSSA), Sapienza University of Rome, 02100 Rieti, Italy.ORCID 0000-0003-0633-360X
Guido AntonelliDepartment of Molecular Medicine, Sapienza University of Rome, 00141 Rome, Italy.ORCID 0000-0002-2533-2939
Ombretta TurrizianiDepartment of Molecular Medicine, Sapienza University of Rome, 00141 Rome, Italy.ORCID 0000-0001-6400-9168

Funding

EU-MUR PE00000007
6 · The paper itself

Abstract

This retrospective study, conducted between September 2023 and October 2025, evaluated age-related pathogen prevalence, seasonal dynamics, and Cycle threshold (Ct) values in nasopharyngeal specimens from hospitalized subjects with suspected acute respiratory infections (ARIs) using the multiplex syndromic panel. A median-based Delta Ct was calculated to define pathogen dominance in co-detections. A total of 2479 nasopharyngeal swabs were analyzed and 54.4% tested positive for at least one pathogen. Overall, the positivity rate and co-detections were found to be significantly higher in pediatric group than in the adult one (

Indexed as

adult respiratory infectionco-infectionCycle thresholddiagnostic stewardshipmultiplex PCRpediatric respiratory infectionrespiratory pathogenrespiratory virus

Identifiers

PMID42513956
PMCPMC13413469

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.