Evidence mapPaperPMID 42514295Full record

ReviewNutrients2026

Nutraceuticals for the Management of Cardiovascular Health: A Mechanistic and Evidence-Based Review Focusing on Atherosclerosis and Hypertension.

Phaniendra Alugoju, Charanraj Goud Alladi, Nyshadham S N Chaitanya, Luxitaa Goenka, Kishoree K Kumaree, Sudarshan Sj, Krishnaswamy Venkataramanasamy Krishnasami Duraisamy, Naeem Ullah

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Phaniendra AlugojuDepartment of Biophysics, Faculty of Science, Palacky University, 779 00 Olomouc, Czech Republic.ORCID 0000-0002-4964-446X
Charanraj Goud AlladiInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Hněvotínská, 779 00 Olomouc, Czech Republic.ORCID 0000-0002-3355-7943
Nyshadham S N ChaitanyaDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad 500046, Telangana, India.ORCID 0000-0002-6332-012X
Luxitaa GoenkaDepartment of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry 605006, India.ORCID 0000-0003-3415-2136
Kishoree K KumareeCollege of Public Health Science, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-0693-6366
Sudarshan SjDepartment of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0003-1278-7069
Krishnaswamy Venkataramanasamy Krishnasami DuraisamyInstitute of Fisheries Biotechnology, Tamilnadu Dr. J. Jayalalithaa Fisheries University, Chennai 603103, Tamil Nadu, India.ORCID 0000-0001-9756-4694
Naeem UllahDepartment of Molecular Biology, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0002-3315-5450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) constitute one of the leading global health burdens, accounting for nearly 50% of all deaths worldwide. Rapid urbanization, lifestyle transitions, psychosocial stress, socioeconomic factors, and changing dietary patterns significantly influence cardiovascular health. Among modifiable risk determinants, atherosclerosis (AS) and hypertension (HTN) are the most critical, interrelated contributors to the onset and progression of CVDs. Nutritional interventions have gained significant global recognition in public health science and clinical practice and are widely regarded as a preventive approach for effective disease management. The goal of the current review is to present evidence from research conducted over the past decade (from 2016 to 2025) supporting the role of nutraceuticals in the management of AS and HTN. This review thoroughly discusses the role of nutraceuticals derived from diverse sources (plants, animals, microorganisms, etc.) from mechanistic aspects to clinical trial endpoints.

Indexed as

AtherosclerosisDietary SupplementsHypertensionAnimalsCardiovascular DiseasesEvidence-Based MedicineHumansRisk Factorsatherosclerosiscardiovascular healthhypertensionnutraceuticals

Identifiers

PMID42514295
PMCPMC13414862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.