Evidence map›Paper›PMID 42514461›Full record

ArticleNutrients2026

Methylsulfonylmethane (MSM) Mitigates Cisplatin-Induced Early Oxidative Testicular Dysfunction Through Modulation of Antioxidant Defense and GPX4 Response.

Pelin İsmailoğlu, Zehra Topal Suzan, Esra Deniz, Adnan Yılmaz, Sibel Mataracı Karakaş, Nevnihal Akbaytürk, Hatice Sevim Nalkıran, İhsan Nalkıran, Ünzile Yaman, Şenay Çakıroğlu and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pelin İsmailoğluDepartment of Anatomy, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53020, Turkey.ORCID 0000-0002-2631-496X
Zehra Topal SuzanDepartment of Histology and Embryology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53020, Turkey.
Esra DenizDepartment of Pharmacology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53020, Turkey.
Adnan YılmazDepartment of Biochemistry, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53020, Turkey.ORCID 0000-0003-4842-1173
Sibel Mataracı KarakaşDepartment of Biochemistry, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53020, Turkey.ORCID 0000-0001-7147-5087
Nevnihal AkbaytürkDepartment of Anatomy, Faculty of Medicine, Giresun University, Giresun 28100, Turkey.ORCID 0000-0003-1953-7572
Hatice Sevim NalkıranDepartment of Medical Biology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53020, Turkey.ORCID 0000-0002-1115-2005
İhsan NalkıranDepartment of Medical Biology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53020, Turkey.ORCID 0000-0002-7246-2592
Ünzile YamanDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir 35620, Turkey.
Şenay ÇakıroğluExperimental Animals Application and Research Center, Recep Tayyip Erdoğan University, Rize 53020, Turkey.
Levent TümkayaDepartment of Histology and Embryology, Faculty of Medicine, Ondokuz Mayıs University, Samsun 55200, Turkey.

Funding

Recep Tayyip Erdoğan University 02026006019418
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntioxidantsCisplatinDimethyl SulfoxideOxidative StressPhospholipid Hydroperoxide Glutathione PeroxidaseSulfonesTestisAnimalsLipid PeroxidationMaleRatsRats, Sprague-DawleyTestosteroneAntioxidantsCisplatindimethyl sulfoneDimethyl Sulfoxideglutathione peroxidase 4, ratPhospholipid Hydroperoxide Glutathione PeroxidaseSulfonesTestosteroneantioxidant defensecisplatinGPX4methylsulfonylmethaneoxidative stressredox homeostasistesticular toxicitytestosterone

Identifiers

PMID42514461
PMCPMC13414715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.