Evidence map›Paper›PMID 42514587›Full record

ArticlePlants (Basel, Switzerland)2026

Co-Overexpression of

Xiaohua Li, Gongqiang Li, Zhiwei Hu, Jiacheng Wang, Yang Chen, Kunhong Zhu, Zichen Huang, Mingyu Wang, Jiayi Sun

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaohua LiCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Gongqiang LiCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Zhiwei HuCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Jiacheng WangCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Yang ChenCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Kunhong ZhuCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Zichen HuangCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Mingyu WangCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.
Jiayi SunCollege of Life and Environmental Science, Wenzhou University, Zhong-Xin Street, Wenzhou 325035, China.

Funding

Zhejiang Provincial Natural Science Foundation KZS2204023
6 · The paper itself

Abstract

Plant-based platforms remain vital for producing anticancer vinca alkaloids. However, one major challenge in plant-based metabolic engineering is that target metabolite yields are often hindered by the presence of multiple competing pathway branches that disperse metabolic flux. To overcome these bottlenecks, we first implemented a competitive branch-point diversion strategy by co-overexpressing

Indexed as

catharanthinecatharanthine synthaseCatharanthus roseusgeissoschizine synthasehairy rootsmetabolic engineeringmetabolomics

Identifiers

PMID42514587
PMCPMC13416060

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.