Evidence map›Paper›PMID 42514878›Full record

ArticlePharmaceutics2026

Icariin-Loaded Milk-Derived Extracellular Vesicles: Protective Effect on Inflammatory Bone Defects via HIF-1α.

Ming Dong, Xinxin Yu, Shuo Liu, Yue Han, Wenqing Han, Lina Wang, Weidong Niu

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ming DongSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Xinxin YuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Shuo LiuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Yue HanSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Wenqing HanSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Lina WangSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Weidong NiuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.

Funding

Department of Science and Technology of Liaoning Province 2025-MSLH-183Educational Department of Liaoning Province LJ212510161008Educational Department of Liaoning Province LJ222410161071Educational Department of Liaoning Province LJ222410161078National Natural Science Foundation of China 82270971National Natural Science Foundation of China 82401094
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bone defectsicariininflammatorysmall extracellular vesicles

Identifiers

PMID42514878
PMCPMC13414905

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.