ReviewPharmaceutics2026
Punctal and Intracanalicular Drug Delivery Systems for Ophthalmic Use: A Narrative Review of Technologies, Clinical Outcomes, and Critical Quality Attributes.
Elena O Bakhrushina, Kseniia S Leonova, Nikita O Belyavsky, Vladimir I Gegechkori, Vasily V Belyaev, Boris B Sysuev, Damir K Salakhetdinov, Ivan I Krasnyuk, Eugenia L Atkova, Vasily D Yartsev
Abstract readReview
In one paragraphReview in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Elena O BakhrushinaDepartment of Pharmaceutical Technology, A.P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia.ORCID 0000-0001-8695-0346 Kseniia S LeonovaDepartment of Pharmaceutical Technology, A.P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia.ORCID 0009-0008-8689-1225 Nikita O BelyavskyDepartment of Pharmaceutical Technology, A.P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia.
Vladimir I GegechkoriDepartment of Pharmaceutical and Toxicological Chemistry, A.P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia.
Vasily V BelyaevDepartment of Industrial Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia.ORCID 0000-0002-3011-9390 Boris B SysuevFaculty of Bioengineering and Bioinformatics, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0002-9933-1808 Ivan I KrasnyukDepartment of Pharmaceutical Technology, A.P. Nelyubin Institute of Pharmacy, I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia.
Eugenia L AtkovaFederal State Budgetary Institution of Science "M.M. Krasnov Research Institute of Eye Diseases" 11A, Rossolimo Street, Moscow 119021, Russia.
Vasily D YartsevFederal State Budgetary Institution of Science "M.M. Krasnov Research Institute of Eye Diseases" 11A, Rossolimo Street, Moscow 119021, Russia.ORCID 0000-0003-2990-8111 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
canaliculitisdexamethasonein situ gelationintracanalicular deliverylacrimal occlusionpunctal plugquality by design (QbD)sustained release
Identifiers
PMID42514908
PMCPMC13414552
What Socratic holds
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