ArticleRSC advances2026
Immunosuppression-free electrospun macroencapsulation devices with immunoprotective features for cell transplantation therapies.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunoisolated cell transplantation offers a promising strategy for multiple endocrine insufficiencies by restoring physiological hormone secretion without systemic immunosuppression. It employs semi-permeable biomaterial encapsulation to permit the exchange of nutrients, oxygen, hormones, and growth factors, while preventing immune-mediated graft rejection. We developed electrospun polyethersulfone (ePES) macroencapsulation devices with controlled nanofibrous architecture to modulate host immune responses and enhance graft protection. Biocompatibility and immunoprotective properties of ePES-based macroencapsulation devices were first evaluated in rats over five weeks. To assess their potential for cell transplantation and immune isolation, ePES-based devices encapsulating allogeneic islets were implanted
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.