Evidence map›Paper›PMID 42516303›Full record

ArticleFrontiers in veterinary science2026

Early cardiovascular and respiratory changes after etorphine immobilization and naltrexone reversal in sheep.

Anna Binetti, Hathaipat Rattanathanya, Friederike Pohlin, Ulrike Auer, J Peter Schramel, Marlies Dolezal, Szilvia Kalogeropoulu, Cosima L Gösele, Lisa Stahl, Lisa J Ebenhofer and 3 more

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Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Anna BinettiAnaesthesiology and Intensive Care, Clinical Centre for Small Animals, Clinical Department for Small Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
Hathaipat RattanathanyaDepartment of Interdisciplinary Life Sciences, Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.
Friederike PohlinDepartment of Interdisciplinary Life Sciences, Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.
Ulrike AuerAnaesthesiology and Intensive Care, Clinical Centre for Small Animals, Clinical Department for Small Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
J Peter SchramelAnaesthesiology and Intensive Care, Clinical Centre for Small Animals, Clinical Department for Small Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
Marlies DolezalPlatform for Bioinformatics and Biostatistics, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
Szilvia KalogeropouluDepartment of Interdisciplinary Life Sciences, Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.
Cosima L GöseleDepartment of Interdisciplinary Life Sciences, Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.
Lisa StahlDepartment of Interdisciplinary Life Sciences, Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.
Lisa J EbenhoferDepartment of Interdisciplinary Life Sciences, Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.
Christina BraunAnaesthesiology and Intensive Care, Clinical Centre for Small Animals, Clinical Department for Small Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
Gabrielle StalderDepartment of Interdisciplinary Life Sciences, Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna, Vienna, Austria.
Martina MosingAnaesthesiology and Intensive Care, Clinical Centre for Small Animals, Clinical Department for Small Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The immediate cardiorespiratory responses to etorphine immobilization and reversal with naltrexone in wildlife are underexplored. Objective: To evaluate the early cardiorespiratory changes after etorphine immobilization and reversal with naltrexone in sheep, as a model for wild ungulates. Methods: Six sheep instrumented with electrical impedance tomography (EIT) belt, arterial and pulmonary arterial catheters were immobilized with intramuscular etorphine (0.05 mg kg Results: Three minutes after etorphine, MPAP increased ( Conclusion: Etorphine immobilization caused early pulmonary hypertension followed by progressive hypoventilation without ventilation redistribution. Naltrexone rapidly restored ventilation, whereas pulmonary vascular effects persisted.

Indexed as

electrical impedance tomographyopioid induced pulmonary hypertensionopioids antagonistultra potent opioidsungulates

Identifiers

PMID42516303
PMCPMC13402195

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.