Evidence mapPaperPMID 42516413Full record

ArticleFrontiers in digital health2026

Geriatric syndromes extraction from discharge summaries: a new dataset, annotation scheme and initial findings.

Imane Guellil, Salomé Andres, Atul Anand, Bruce Guthrie, Fahrurrozi Rahman, Abul Hasan, Huayu Zhang, Honghan Wu, Beatrice Alex

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Article in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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9 authors.

Imane GuellilAdvanced Care Research Centre - Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Salomé AndresAdvanced Care Research Centre - Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Atul AnandAdvanced Care Research Centre - Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Bruce GuthrieAdvanced Care Research Centre - Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Fahrurrozi RahmanAdvanced Care Research Centre - Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Abul HasanInstitute of Health Informatics, University College London (UCL), London, United Kingdom.
Huayu ZhangAdvanced Care Research Centre - Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Honghan WuSchool of Health & Wellbeing, University of Glasgow, Glasgow, United Kingdom.
Beatrice AlexAdvanced Care Research Centre - Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.

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6 · The paper itself

Abstract

Introduction: Geriatric syndromes (GS), such as falls, dementia, delirium and malnutrition, are complex clinical conditions affecting older adults which involve multiple organ systems and have major impact on quality of life and care. GS cut across disease categories, and are poorly represented in structured electronic health records. Natural language processing (NLP) offers an opportunity to extract valuable GS-related information from unstructured clinical text, such as hospital discharge summaries. However, the lack of high-quality annotated datasets limits the effectiveness of NLP models in this domain. This study introduces a manually annotated corpus designed for GS detection, enabling more accurate identification and classification of GS. Methods: We developed a comprehensive and detailed annotation scheme to label 12 common GS from hospital discharge summaries, incorporating key attributes such as diagnosis type, negation and event occurrence. The corpus consists of 2,040 manually annotated discharge summaries from National Health Service (NHS) Lothian hospitals in Scotland. To assess the effectiveness of NLP in extracting GS, we experimented with multiple pretrained transformer-based models, including base BERT (general-domain), BioBERT (biomedical-domain), BioClinicalBERT (clinical-domain) and BERT-cased (the cased English BERT checkpoint). The models were fine-tuned and tested for two types of tasks: named entity recognition (NER) and document-level labelling. We also considered an extra task of detecting contextual information with each GS mention (e.g., history, suspected, in-hospital). When context information is considered, two new tasks are called NER-C and DL-C, for NER and document-level labelling with context respectively. Results: Our evaluation showed that, for the document-level labelling task, BERT-cased achieved the highest F1-score (0.897) and BioClinicalBERT performed best when negation was considered (F1-score: 0.888). For the NER task, BioClinicalBERT and BERT-cased achieved an F1-score of 0.883. Frailty (F1 Discussion: This study demonstrates the effectiveness of NLP for extracting geriatric syndromes from unstructured clinical text and introduces a manually annotated corpus with detailed guidelines to support this task. The results also show that model performance is strongly shaped by dataset characteristics. More frequent and lexically clearer syndromes, such as frailty, falls and delirium, achieved the strongest results, whereas rarer categories and low-frequency attribute combinations, such as suspected, referral and some negated or context-specific labels, were harder to learn and yielded lower and less stable scores. Likewise, fine-grained annotation was more challenging than coarse-grained annotation because it increases label sparsity and requires the model to distinguish subtle contextual differences, such as current vs. historical mentions, implicit mentions and in-hospital onset. Entity-level extraction was further affected by discontinuous and overlapping mentions, which are common in clinical narratives and make boundary detection harder, whereas document-level aggregation reduced the impact of these local errors and therefore produced higher scores. These findings underline that data distribution, annotation complexity and mention structure directly influence model performance, and should be central considerations in future work on geriatric syndrome extraction.

Indexed as

annotation guidelinescorpus annotationgeriatric syndromesnamed entity recognitionnatural language processingNLP

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PMID42516413
PMCPMC13402457

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.