Evidence map›Paper›PMID 42517620›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2026

Compendium of RNA modifications for bacterial stress adaptation.

Siobhan A Cusack, Sebastián Riquelme-Barrios, Luis Rivera-Montero, Leonardo Vásquez-Camus, Dania Devassy, Kirsten Jung

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Siobhan A Cusack *Faculty of Biology, Microbiology, Ludwig-Maximilians-Universität München, Martinsried, Germany.ORCID 0009-0009-3597-6437
Sebastián Riquelme-Barrios *Faculty of Biology, Microbiology, Ludwig-Maximilians-Universität München, Martinsried, Germany.ORCID 0000-0001-9995-0804
Luis Rivera-MonteroFaculty of Biology, Microbiology, Ludwig-Maximilians-Universität München, Martinsried, Germany.ORCID 0000-0001-8739-7466
Leonardo Vásquez-CamusFaculty of Biology, Microbiology, Ludwig-Maximilians-Universität München, Martinsried, Germany.ORCID 0009-0002-7096-350X
Dania DevassyFaculty of Biology, Microbiology, Ludwig-Maximilians-Universität München, Martinsried, Germany.ORCID 0009-0005-5437-0992
Kirsten JungFaculty of Biology, Microbiology, Ludwig-Maximilians-Universität München, Martinsried, Germany.ORCID 0000-0003-0779-6841

Funding

Deutsche Forschungsgemeinschaft 325871075 (SFB 1309) (A07), 464582101 (Ju270/21-1)
6 · The paper itself

Abstract

SUMMARYRNA modifications in the tRNA, rRNA, and mRNA constitute a widespread layer of post-transcriptional gene regulation, commonly known as the epitranscriptome. In bacteria, tRNA and rRNA modifications are well documented and play essential roles in tRNA folding, rRNA maturation, translation, and peptidyl transfer. Although mRNA modifications have been extensively characterized in eukaryotes, their functional implications for mRNA fate in prokaryotes remain uncertain, and their identities and locations are the subject of an emerging field of research. Importantly, RNA modification is a dynamic process, and variation in the presence and abundance of these modifications has significant consequences for bacterial physiology. Here, we discuss current knowledge of modified RNA nucleotides in bacteria, with a particular focus on their roles in bacterial adaptation to environmental stress.

Indexed as

Adaptation, PhysiologicalBacteriaBacterial Physiological PhenomenaRNA, BacterialRNA Processing, Post-TranscriptionalStress, PhysiologicalEpitranscriptomeGene Expression Regulation, BacterialRNA, MessengerRNA MethylationRNA, RibosomalRNA, TransferRNA, BacterialRNA, MessengerRNA, RibosomalRNA, Transferenvironmental stressepitranscriptomemRNArRNAtRNA

Identifiers

PMID42517620
PMCPMC13602947

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.