SynthesisFrontiers in public health2026
Effects of combined aerobic and resistance training on cardiometabolic risk factors in overweight/obese adolescents: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objective: Implementing scientific exercise interventions during childhood and adolescence holds long-term value for vascular protection. This study aimed to systematically evaluate the actual effects of combined aerobic and resistance training (CART) on glucose metabolism parameters, lipid profiles, and blood pressure dynamics in adolescents with overweight or obesity. Methods: Electronic databases including PubMed, Web of Science, Embase, The Cochrane Library, and Scopus were searched from inception up to May 13, 2026, to collect randomized controlled trials (RCTs) investigating CART interventions in adolescents with overweight or obesity. Data analysis was performed using R software. Mean difference (MD) and 95% confidence intervals (CI) were uniformly employed as effect measures, with change-from-baseline values entered into the models. Hierarchical subgroup analyses based on control group type were conducted utilizing the Hartung-Knapp-Sidik-Jonkman (HKSJ) random-effects model, and the quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Results: A total of 12 RCTs were included. Regarding glucose metabolism, fasting insulin showed a significant reduction in the CART vs. non-exercise control (CON) subgroup (MD = -17.90 μU/mL, 95% CI: -26.04 to -9.76, Conclusion: Current evidence indicates that CART demonstrates statistically significant improvements in fasting insulin, SBP, DBP, and adiponectin levels in adolescents with overweight or obesity; however, due to limitations including high variability in intervention protocols, absence of blinding, and regional concentration of included studies, the overall quality of evidence is low, and the actual clinical meaningfulness still requires cautious interpretation. All conclusions must be interpreted based on the classification of control group activity status. Future research urgently needs to adopt standardized combined training protocols, establish consistent comparator definitions, and conduct large-sample RCTs with longer follow-up periods for confirmation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.