ArticleFrontiers in medicine2026
Prone position ventilation combined with high-flow nasal cannula oxygen therapy in patients with pulmonary infection: a retrospective study on evidence-based nursing practice.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Pulmonary infections are a common and serious clinical condition, particularly affecting critically ill patients, and effective respiratory management is crucial for recovery. This study examined the clinical and nursing outcomes associated with prone position ventilation (PPV) combined with high-flow nasal cannula (HFNC) oxygen therapy in patients with pulmonary infection. Methods: We conducted a retrospective analysis of 200 patients with pulmonary infection admitted to two tertiary hospitals between January 2022 and January 2024. On the basis of the respiratory support actually received during hospitalization (non-randomized allocation), patients were assigned to an observation group ( Results: Over the first 72 h, the observation group showed greater improvements in PaO Conclusion: In this retrospective, non-randomized cohort, PPV combined with HFNC oxygen therapy was associated with better respiratory outcomes, fewer complications, shorter hospitalization and higher nurse-assessed comfort and compliance than conventional oxygen therapy. Because treatment allocation was not randomized, these associations cannot establish causality, and prospective randomized trials are needed to confirm the findings in larger cohorts.
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