Evidence map›Paper›PMID 42519803›Full record

ArticleFrontiers in medicine2026

Differential effects of propofol and dexmedetomidine on explicit and implicit memory after sedation: a retrospective study.

Bojun Zhang, Fang Jia, Ping Li

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bojun Zhang *Department of Anesthesia, Tianjin Hospital, Tianjin, China.
Fang Jia *Department of Anesthesia, Tianjin Hospital, Tianjin, China.
Ping LiDepartment of Anesthesia, Tianjin Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare the effects of dexmedetomidine and propofol on early postoperative cognitive function and safety in patients undergoing short-term surgical sedation. Methods: This retrospective cohort study included 295 adult patients who received intravenous sedation during non-cardiac surgery (January 2023-January 2025). Patients were divided into dexmedetomidine ( Results: On postoperative day 1, the dexmedetomidine group showed higher RAVLT delayed recall scores (8.08 ± 3.06 vs. 7.24 ± 2.82, Conclusion: In this short-term sedation cohort, dexmedetomidine was associated with better explicit memory but slower processing speed and longer recovery versus propofol, with distinct safety profiles. The clinical significance of these small cognitive differences remains uncertain, and prospective validation is needed.

Indexed as

calmdexmedetomidinepostoperative cognitive impairmentpropofolretrospective cohort study

Identifiers

PMID42519803
PMCPMC13381631

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.