ArticleNature communications2026
The genetics of fibromyalgia and its relationships to psychiatric and medical traits.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A neurogenetic blueprint for fibromyalgia.Nature reviews. Rheumatology · 2026Article
- The genetic architecture of fibromyalgia across 2.5 million individuals.Nature medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
We explore the genetic mechanisms underlying fibromyalgia, a chronic heritable syndrome. We conduct genome-wide association studies (GWAS) of fibromyalgia in European, African, and Latin American ancestry subjects, combining data from several cohorts (85,139 cases; 1,642,433 controls). We also conduct a multi-trait analysis of GWAS (MTAG), leveraging pain GWAS to enhance power for fibromyalgia analyses. We apply a series of methods to analyze genetic association between fibromyalgia and psychological and physiological phenotypes. We find 10 genomic loci that are associated with fibromyalgia in European ancestry subjects, one in African, 12 cross-ancestry, and 45 in the European ancestry MTAG; most of these were previously associated with pain, cognitive function, autoimmune response, or general health measures. We show a moderate negative genetic correlation between fibromyalgia and physical activity, and strong genetic correlations with chronic pain, post-traumatic stress disorder, and depression (r
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.