Evidence map›Paper›PMID 42523595›Full record

ArticleFrontiers in immunology2026

Reorganization and functional divergence of the CD4+ memory T cell compartment in hidradenitis suppurativa.

Laura Casals-Diaz, Jorge Romaní, Abir Ezzaanouni, Madalina Raducu, Cristina Vila, Lluís Boix, Amadeu Gavaldà, Antonio Guilabert

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Laura Casals-DiazDisease Biology Department, Almirall R&D Center, Sant Feliu de Llobregat, Barcelona, Spain.
Jorge RomaníHospital General de Granollers, Dermatology, Granollers, Barcelona, Spain.
Abir EzzaanouniDisease Biology Department, Almirall R&D Center, Sant Feliu de Llobregat, Barcelona, Spain.
Madalina RaducuDisease Biology Department, Almirall R&D Center, Sant Feliu de Llobregat, Barcelona, Spain.
Cristina VilaDisease Biology Department, Almirall R&D Center, Sant Feliu de Llobregat, Barcelona, Spain.
Lluís BoixDisease Biology Department, Almirall R&D Center, Sant Feliu de Llobregat, Barcelona, Spain.
Amadeu GavaldàDisease Biology Department, Almirall R&D Center, Sant Feliu de Llobregat, Barcelona, Spain.
Antonio GuilabertHospital General de Granollers, Dermatology, Granollers, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with poorly understood and complex pathophysiology with interplay between many immune and stromal cells. While the T cell infiltrate in HS is well-documented, the relationship between systemic memory T cells and those within the cutaneous microenvironment has yet to be fully elucidated. We performed a comparative analysis of skin and peripheral blood mononuclear cells (PBMCs) samples from HS patients and healthy controls using flow cytometry to evaluate T cell subsets and their cytokine profile with focus on TNF-α, IFN-γ, IL-17A. Within the memory compartment, CD4+ central memory T cells (T

Indexed as

CD4-Positive T-LymphocytesHidradenitis SuppurativaImmunologic MemoryMemory T CellsAdultCytokinesFemaleHumansMaleMiddle AgedSkinT-Lymphocyte SubsetsYoung AdultCytokinesCCR7central memory T cellshidradenitis suppurativaresident memory T cellsTh17

Identifiers

PMID42523595
PMCPMC13407087

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.