ArticleFrontiers in medicine2026
The effectiveness of 0.05% cyclosporine A combined with deproteinized calf blood extract eye gel in the treatment of dry eye disease after pterygium surgery.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To investigate the effectiveness of combining 0.05% cyclosporine A (CsA) eye drops and deproteinized calf blood extract (DCBE) eye gel for treating dry eye disease (DED) following pterygium surgery. Methods: This retrospective study included 64 patients (32 in each group) who underwent pterygium excision with autologous limbal stem cell transplantation. The experimental group received 0.05% CsA eye drops and DCBE eye gel, while the control group received DCBE eye gel alone. Ocular parameters were assessed preoperatively and at 1, 2, and 3 months postoperatively. Results: Repeated-measures ANOVA demonstrated significant interaction effects between time and group for tear fluorescein break-up time (TFBUT; Conclusion: The combination of 0.05% CsA eye drops and DCBE eye gel is more effective than DCBE eye gel alone in improving tear film stability and treating DED following pterygium surgery, with good safety and no recurrence observed.
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