Evidence map›Paper›PMID 42525192›Full record

ArticleApplied biochemistry and biotechnology2026

Estimated Binding Affinities of Polyphenolic Compounds into the Human Peroxiredoxin 5 and the SARS-CoV-2 main Protease Binding Sites: In Silico Approach.

El Hassane Anouar, Magdy M D Mohammed, Zuhra Bashir Trabalsiy, Insaf Filali, Abdulrahman I Alharthi, Amany M A Osman

Abstract read
PubMed Publisher
In one paragraph

Article in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

El Hassane AnouarDepartment of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia. anouarelhassane@yahoo.fr.ORCID http://orcid.org/0000-0001-9240-7163
Magdy M D MohammedPharmacognosy Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Dokki, Cairo, 12622, Egypt.
Zuhra Bashir TrabalsiyDepartment of Biology, Faculty of Education, Elmergib University, Al- Khums, Libya.
Insaf FilaliDepartment of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
Abdulrahman I AlharthiDepartment of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
Amany M A OsmanChemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam, 51132, Egypt.

Funding

This study is supported via funding from Prince Sattam bin Abdulaziz University project number (PSAU/2025/01/32964) PSAU/2025/01/32964
6 · The paper itself

Abstract

Polyphenols are secondary metabolites of plants. They have potential health benefits as antioxidants and protection against the development of cancers, cardiovascular disease, and diabetes. Herein, the inhibitory potential of a series of 35 simple phenols, flavone, flavonol, flavanone, dihyrdoflavanol, flavan-3-ol, anthocyanidin, isoflavone, chalcone, silybins polyphenolics against (i) the main protease of (M

Indexed as

Antioxidant activityDFTMolecular dockingMolecular dynamicsPolyphenolsSARS-CoV-2

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.