Evidence map›Paper›PMID 42526437›Full record

ArticleCell chemical biology2026

TRPM8 is a non-canonical target of 7-nitrobenzodiazepines.

Logan Elkin, Evgeny G Chulkov, Jonathan D Enders, Anthony D Menzel, Sang-Kyu Park, Cheryl L Stucky, Jonathan S Marchant

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Logan ElkinDepartment of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Evgeny G ChulkovDepartment of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Jonathan D EndersDepartment of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Anthony D MenzelDepartment of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Sang-Kyu ParkDepartment of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Cheryl L StuckyDepartment of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Jonathan S MarchantDepartment of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: jmarchant@mcw.edu.

Funding

Resolving the properties of schistosome TRPMPZQ, the target of the anthelmintic drug praziquantelR01AI145871 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI Wei Liu, JONATHAN S MARCHANT · 2020 to 2026
$3.1M
NIAID NIH HHS R01 AI145871
6 · The paper itself

Abstract

Benzodiazepines are widely prescribed therapeutics whose actions are primarily attributed to the modulation of GABA

Indexed as

burning mouth disorderneuropathypainpolypharmacologyTRP channel

Identifiers

PMID42526437
PMCPMC13426060

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.