ArticleNature2026
A global view of human centromere variation and evolution.
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In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Optimized Genome-Wide Profiling of Centromeric Chromatin Complexes by ChIP-seq.Current protocols · 2026Article
- HPRC2: A human pangenome reference with near-complete coverage of common genetic variation.bioRxiv : the preprint server for biology · 2026Article
- Personalized reference genome-based pipeline reveals comprehensive haplotype-resolved views of cancer genomes.bioRxiv : the preprint server for biology · 2026Article
- HOROSCOPE: Decoding human centromere architecture from short reads usingbioRxiv : the preprint server for biology · 2026Article
- Population-scale Y chromosome assemblies reveal recurrent remodeling within constrained architectures.bioRxiv : the preprint server for biology · 2026Article
- A complete human pancreatic cancer genome.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
- Update of
Authors and funding
16 authors.
Shenghan Gao *Department of Genetics, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-3810-6527
Keisuke K Oshima *Department of Genetics, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Shu-Cheng ChuangDepartment of Genetics, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Mark LoftusDepartment of Genetics & Biochemistry, Clemson University, Clemson, SC, USA.ORCID http://orcid.org/0000-0002-6279-6855
Tamara A PotapovaStowers Institute for Medical Research, Kansas City, MO, USA.ORCID http://orcid.org/0000-0003-2761-1795
Annalaura MontanariDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Bari, Italy.
David S GordonDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Twin Cities, MN, USA.ORCID http://orcid.org/0000-0001-6552-4022
Zikun YangBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
Human Genome Structural Variation Consortium
Human Pangenome Reference Consortium
Yafei MaoBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.ORCID http://orcid.org/0000-0002-9648-4278
PingHsun HsiehDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Twin Cities, MN, USA.ORCID http://orcid.org/0000-0001-8294-6227
Jennifer L GertonStowers Institute for Medical Research, Kansas City, MO, USA.ORCID http://orcid.org/0000-0003-0743-3637
Miriam K KonkelDepartment of Genetics & Biochemistry, Clemson University, Clemson, SC, USA.ORCID http://orcid.org/0000-0002-3190-1667
Mario VenturaDepartment of Biosciences, Biotechnology and Environment, University of Bari Aldo Moro, Bari, Italy.ORCID http://orcid.org/0000-0001-7762-8777
Glennis A LogsdonDepartment of Genetics, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. glogsdon@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0003-2396-0656
Funding
The WashU-UCSC-EBI Human Genome Reference Center."U41HG010972 · NHGRI · WASHINGTON UNIVERSITY · PI Ira M Hall, Heng Li · 2019 to 2026
$24.9MELSI Administrative Supplement - Center for Human Reference Genome DiversityU01HG010971 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI EICHLER, EVAN, JARVIS, ERICH D · 2019 to 2023
$18.4MStatistical Methods for Gene Regulatory Analysis From Single Cell Genomics DataP20GM139769 · NIGMS · CLEMSON UNIVERSITY · PI ANHOLT, ROBERT R. H, ARNO, GAVIN · 2021 to 2025
$10.8MTelomere-to-telomere assemblies of human genomesR01HG011274 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Karen Hayden Miga · 2020 to 2026
$4.5MMaintaining the integrity of a genomeR01CA266339 · NCI · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI JENNIFER L GERTON · 2022 to 2026
$1.9MTools for comprehensive variant characterization using the pangenomeU01HG013748 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI LI, HENG, MARSCHALL, TOBIAS · 2024 to 2024
$1.7MBuilding Tools and Community to Make Pangenomes AccessibleU01HG013760 · NHGRI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI GARRISON, ERIK · 2024 to 2024
$1.6MTooling for accurately studying the epigenome along the human pangenome referenceU01HG013744 · NHGRI · UNIVERSITY OF WASHINGTON · PI STERGACHIS, ANDREW BEN · 2024 to 2024
$1.4MIntegrating the reference pangenome with biobank-scale data for complex trait analysisU01HG013755 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GYMREK, MELISSA · 2024 to 2024
$1.3MHuman centromere variation and functionR00GM147352 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Glennis Amelia Logsdon · 2024 to 2026
$747kThe fitness effects of de novo structural variantsR00HG011041 · NHGRI · UNIVERSITY OF MINNESOTA · PI HSIEH, PINGHSUN · 2023 to 2025
$729kDeciphering genome integrity maintenance using cytogenomicsR50CA305001 · NCI · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI Tamara A Potapova · 2025 to 2026
$251kNCI NIH HHS R01 CA266339NCI NIH HHS R50 CA305001NHGRI NIH HHS R00 HG011041NHGRI NIH HHS R01 HG011274NHGRI NIH HHS U01 HG010971NHGRI NIH HHS U01 HG013744NHGRI NIH HHS U01 HG013748NHGRI NIH HHS U01 HG013755NHGRI NIH HHS U01 HG013760NHGRI NIH HHS U41 HG010972NIGMS NIH HHS P20 GM139769NIGMS NIH HHS R00 GM147352
Abstract
Centromeres are essential chromosomal regions that ensure accurate chromosome segregation during cell division, yet their highly repetitive sequence has historically hindered their complete assembly and characterization
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What Socratic holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.