Evidence map›Paper›PMID 42527741›Full record

ArticleSleep & breathing = Schlaf & Atmung2026

Relationship between MSpO

Ying-Hui Gao, Xin Xue, Dong Rui, Wei-Meng Cai, Yao Ma, Kun Qian, Li-Bo Zhao, Yu-Ying Yang, Ming-Ru Zhang, Zhe Zhao and 3 more

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ying-Hui Gao *PKU-UPenn Sleep Center, Peking University International Hospital, Beijing, China.
Xin XueDepartment of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China.
Dong RuiDepartment of Pulmonary and Critical Care Medicine of the Second Medical Center &, National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Wei-Meng CaiDepartment of Pulmonary and Critical Care Medicine of the Second Medical Center &, National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Yao MaDepartment of Pulmonary and Critical Care Medicine of the Second Medical Center &, National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Kun QianThe Senior Cadres Activity Center of PLA, Beijing, China.
Li-Bo ZhaoBeijing Institute of Heart, Lung, and Blood Vessel Disease, Anzhen Hospital, Capital Medical University, Beijing, China.
Yu-Ying YangMedical College, Yanan University, Yanan, China.
Ming-Ru ZhangMedical College, Yanan University, Yanan, China.
Zhe ZhaoCardiology Department of the Second Medical Center &, National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Wei-Hao XuDepartment of Geriatrics, Guangdong Provincial Peoples Hospital, Guangdong Provincial Geriatrics Institute, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Xiao-Shun QianDepartment of Pulmonary and Critical Care Medicine, Shenmu Hospital, The Affiliated Shenmu Hospital of Northwest University, Shaanxi, China.
Lin Liu *Department of Pulmonary and Critical Care Medicine of the Second Medical Center &, National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China. liulin715@qq.com.

Funding

National Natural Science Foundation of China 82570124
6 · The paper itself

Abstract

objectiveThis study explored risk factors associated with depressive symptoms in older patients with obstructive sleep apnea (OSA) and assessed correlations of mean pulse oxygen saturation (MSpO

methodsIn total, 1,085 older patients diagnosed with OSA via polysomnography (PSG) were included. Based on scores from the 12-item Geriatric Depression Scale (GDS-12), participants were classified into two subgroups to identify depressive symptom-related risk factors. Logistic regression analysis, restricted cubic splines, and subgroup analyses were performed to evaluate correlations of MSpO

resultsDepressive symptoms were observed in 139 patients (12.8% of the sample). Logistic regression analysis indicated that age (per 1-year increase, odds ratio [OR] = 1.11, 95% confidence interval [CI]: 1.08-1.14; P < 0.001), smoking (OR = 1.66, 95% CI: 1.02-2.69; P = 0.041), MSpO₂ (per 1% increase, OR = 0.90, 95% CI: 0.85-0.94; P < 0.001), diabetes mellitus (OR = 1.61, 95% CI: 1.03-2.51; P = 0.038), and renal dysfunction (OR = 2.26, 95% CI: 1.10-4.66; P = 0.027) were significantly associated with depressive symptoms. Additionally, sleep parameters including AHI, ODI, and LSpO₂ were independently associated with depressive symptoms. Restricted cubic splines suggested a linear correlation between MSpO₂ and depressive symptoms (nonlinear P = 0.38). Compared with patients in the highest category (MSpO₂ ≥ 95.0%), those in the lowest category (MSpO₂ ≤ 91.7%) showed increased depressive symptom risk (OR = 2.25, 95% CI: 1.34-3.78, P = 0.002). Subgroup analyses confirmed this linear relationship.

conclusionA linear correlation exists between MSpO

Indexed as

Depressive DisorderOxygen SaturationSleep Apnea, ObstructiveAgedAged, 80 and overComorbidityCorrelation of DataCross-Sectional StudiesFemaleHumansMaleMiddle AgedPolysomnographyRisk FactorsStatistics as TopicDepressive symptomsMean pulse oxygen saturationObstructive sleep apneaOlder adults

Identifiers

PMID42527741

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.