ArticleFrontiers in neurology
Feasibility and preliminary signal of cerebellar intermittent theta burst stimulation for static balance in cerebellar ataxia: a pilot study.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study explored the short-term effects of 50 Hz cerebellar intermittent theta burst stimulation (iTBS) on static balance and prefrontal cortical activation in patients with cerebellar ataxia (CA). Ten patients with CA (4 males; mean age, 57.6 ± 9.1 years) underwent iTBS over the bilateral cerebellum for five consecutive days (8 min/session, 80% active motor threshold); static balance was assessed using a Balance Trainer 4 (BT4) under eyes-open (EO) and eyes-closed (EC) conditions at baseline (V0), immediately post-intervention (V1), and 6 weeks post-treatment (V2). Clinical scales (K-SARA, K-MBI, SF-36-K) and functional near-infrared spectroscopy (fNIRS) during a dual-task toe-tapping paradigm (motor + mental subtraction) were also administered to evaluate motor and cognitive responses. Significant, albeit transient, improvements in postural balance were observed at V1 relative to V0: under EO conditions, anterior-posterior sway (ΔY) and total displacement (Δd) decreased significantly (
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