ReviewFrontiers in cardiovascular medicine2026
The regulatory mechanisms and translational applications of non-coding RNA in SARS-CoV-2 infection-related cardiovascular pathology.
Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
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Abstract
SARS-CoV-2 infection not only leads to severe respiratory diseases but also has a significant impact on the cardiovascular system, inducing acute cardiac injury and various long-term cardiovascular complications. Non-coding RNAs (ncRNAs), as key molecules in gene expression regulation, exhibit important regulatory roles in viral infections and cardiovascular pathological processes. Current research indicates that ncRNAs such as miRNA, lncRNA, and circRNA participate in the occurrence and development of cardiac injury related to SARS-CoV-2 infection by regulating apoptosis, metabolic reprogramming, and cell communication. However, there are still many challenges and unresolved mysteries regarding their specific regulatory networks and clinical applications. This review systematically summarizes the expression changes and functional characteristics of ncRNAs in COVID-19-related cardiovascular diseases, focusing on their potential as biomarkers and therapeutic targets, and combining the latest multi-omics data and cutting-edge technologies to anticipate the development direction of precise interventions and personalized treatments.
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