ArticleFood science & nutrition2026
Effects of Exogenous Monosodium Glutamate on GABA Accumulation and Volatile/Nonvolatile Metabolites in Black Highland Barley.
Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
γ-Aminobutyric acid (GABA) is a functional amino acid with multiple health benefits; however, the mechanism of its enrichment in black highland barley, particularly through precursor supplementation, has not been fully elucidated. In this study, the effects of exogenous monosodium glutamate (MSG) on GABA accumulation and metabolite regulation were investigated. Precursor types and germination conditions were optimized using a single-factor approach, and under the optimal MSG concentration, ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS), gas chromatography-mass spectrometry (GC-MS), and gas chromatography-ion mobility spectrometry (GC-IMS) were employed to profile amino acids, fatty acids, and volatile and nonvolatile metabolites. The results showed that MSG addition significantly enhanced GABA accumulation compared with glutamic acid (
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