ReviewChemical & biomedical imaging2026
Research on the Application of Fluorescent Probes in Revealing the Mechanism of Cerebral Ischemia-Reperfusion Injury.
Review in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Advances in galactose-based small-molecule hepatocyte-targeting probes for detecting biomarkers in hepatocellular carcinoma.Frontiers in chemistry · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite being a key treatment for ischemic strokea brain injury with high incidence, mortality, disability, and recurrence ratesreperfusion therapy can cause secondary cerebral ischemia-reperfusion injury (CIRI). During the course of CIRI, a large amount of reactive oxygen species (ROS) and reactive nitrogen species (RNS) burst out, causing cellular redox imbalance, followed by cellular oxidative stress, and ultimately leading to neuronal death. ROS and reactive sulfur species (RSS) are two important oxidizing and reducing substances in the body, playing a significant role in regulating redox homeostasis. Therefore, real-time monitoring of their levels and dynamic changes can provide effective strategies for alleviating CIRI. However, organic small molecule probes have deficiencies in selectivity and blood-brain barrier (BBB) permeability, making real-time monitoring of active species changes during CIRI in the brain more difficult. Therefore, this review summarizes the application and research progress of organic small molecule fluorescent probes in the field of CIRI in the past five years, and classifies them according to design strategies, which is expected to provide guidance for the subsequent development of organic small molecule fluorescent probes for CIRI and expand their application in the biomedical field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.