Evidence map›Paper›PMID 42531020›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Ubiquitination plays a key role in an insecticide resistance fitness cost.

Jinyu Hu, Buli Fu, Qi Su, Xindi Guo, Chengjia Zhang, Qimei Tan, Rong Zhang, Hantang Lu, Peipan Gong, Shaonan Liu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jinyu Hu *State Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0009-0000-4002-5921
Buli Fu *State Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Qi Su *Ministry of Agriculture and Rural Affairs Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River (Co-construction by Ministry and Province), Hubei Engineering Technology Center for Forewarning and Management of Agricultural and Forestry Pests, College of Agriculture, Yangtze University, Jingzhou 434025, Hubei, China.
Xindi Guo *Institute of Food and Nutrition Development, Ministry of Agriculture and Rural Affairs, Beijing 100081, China.ORCID 0009-0007-0368-8065
Chengjia Zhang *State Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Qimei TanState Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Rong ZhangState Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Hantang LuState Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Peipan GongState Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0009-0003-2391-8906
Shaonan LiuState Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Xuguo ZhouDepartment of Entomology, School of Integrative Biology, College of Liberal Arts and Sciences, University of Illinois Urbana-Champaign, Urbana, IL 61801-3795.ORCID 0009-0008-1857-2337
Ralf NauenCrop Science Division, Bayer AG, Monheim 40789, Germany.ORCID 0000-0002-7525-8589
Youjun ZhangState Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0000-0003-3508-6695
Chris BassDepartment of Biosciences, College of Life and Environmental Sciences, University of Exeter, Penryn TR10 9FE, Cornwall, United Kingdom.
Xin YangState Key Laboratory of Vegetable Biobreeding, Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0000-0001-8159-6923

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ubiquitination is an essential posttranslational modification in eukaryotes, which plays a fundamental role in numerous important biological functions. However, the role of ubiquitination in the evolution of adaptive traits in insects remains poorly understood. Here, we reveal the role of ubiquitination in insecticide resistance and its associated fitness cost in the whitefly pest,

Indexed as

Genetic FitnessHemipteraInsecticide ResistanceUbiquitinationAnimalsInsecticidesInsect ProteinsUbiquitin-Protein LigasesInsecticidesInsect ProteinsUbiquitin-Protein LigasesE1-1/E2-3/TRIM37 cascadeE3 ubiquitin ligaseinsecticide resistancereproductive costubiquitination

Identifiers

PMID42531020
PMCPMC13439105

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.