Evidence map›Paper›PMID 42533203›Full record

ArticleJournal of fluorescence2026

A Fluorescent Probe for Carboxylesterases Detection in Estradiol Valerate-Treated Inflammation Alleviation.

Wenqiang Jiang, Zhenhua Zhong, Lubing Tang, Yuqiang Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenqiang JiangDepartment of Breast Surgery, Womens and Childrens Hospital Affiliated to Ningbo University, Ningbo, 315000, China.
Zhenhua ZhongDepartment of Breast Surgery, Womens and Childrens Hospital Affiliated to Ningbo University, Ningbo, 315000, China.
Lubing TangDepartment of Breast Surgery, Womens and Childrens Hospital Affiliated to Ningbo University, Ningbo, 315000, China.
Yuqiang ChenDistrict 6, General Surgery Ward, First Affiliated Hospital of Jiamusi University, Jiamusi, 154002, China. nbyymrj@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, a fluorescent probe PIPM-CE was developed for the carboxylesterases (CE) detection in the estradiol valerate (EV)-treated inflammation alleviation. Under the excitation at 368 nm, the notable fluorescence signal was found at 479 nm. The confirmation on the working conditions suggested the rapid recognition reaction process and stable reporting signal. The probe also showed relatively high sensitivity, high specificity, and low cytotoxicity. By the construction of the basic correlation between the CE level and the fluorescence signal intensity, PIPM-CE achieved imaging the EV-treated inflammation alleviation on both the rational therapeutical treatment and the avoidance of overdose-caused disorder. This work was meaningful for the precise monitoring of the hormone therapies.

Indexed as

Carboxylic Ester HydrolasesEstradiolFluorescent DyesInflammationAnimalsFluorescent Chemosensor CompoundsHumansMiceCarboxylic Ester HydrolasesEstradiolFluorescent Chemosensor CompoundsFluorescent DyesCarboxylesterasesCellular imagingEstradiol valerateFluorescent probeInflammation alleviation

Identifiers

PMID42533203

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.