Evidence map›Paper›PMID 42534150›Full record

ReviewWorld journal of radiology2026

Radiolabeled exosomes for theranostics: Personalized tailored therapy through imaging.

Soumya Deep Phadikar, Aliza Hyder, Ramya Lakshmi Rajendran, Anand Krishnan, Chae Moon Hong, Prakash Gangadaran, Byeong-Cheol Ahn

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Soumya Deep PhadikarDepartment of Chemistry and Chemical Biology, Indian Institute of Technology (ISM), Dhanbad 826004, Jharkhand, India.
Aliza HyderDepartment of Biological Sciences, Birla Institute of Technology and Science, Pilani (Hyderabad Campus), Hyderabad 500078, Telengana, India.
Ramya Lakshmi RajendranBK21 FOUR KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents, Department of Biomedical Sciences, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
Anand KrishnanPrecision Medicine and Integrated Nano-Diagnostics (P-MIND) Research Laboratory, Department of Haematology and Cell Biology, School of Pathology, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.
Chae Moon HongDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
Prakash GangadaranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.
Byeong-Cheol AhnDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiolabeled exosomes have emerged as a transformative platform at the intersection of nanomedicine, molecular imaging, and precision theranostics. These nanoscale extracellular vesicles exhibit intrinsic biocompatibility, low immunogenicity, and inherent targeting capabilities, making them highly attractive for both diagnostic and therapeutic applications. The integration of radiochemistry with exosome biology enables noninvasive, real-time tracking of biodistribution, pharmacokinetics, and target engagement using advanced imaging modalities such as positron emission tomography and single-photon emission computed tomography. This minireview comprehensively summarizes current radiolabeling strategies for exosomes, including direct and indirect approaches, highlighting their advantages, limitations, and impact on vesicle integrity and imaging accuracy. Furthermore, we discuss key imaging platforms,

Indexed as

BiodistributionDrug deliveryExtracellular vesiclesNanomedicinePharmacokineticsPositron emission tomography imagingRadiolabeled exosomesSingle-photon emission computed tomography imagingTheranostics

Identifiers

PMID42534150
PMCPMC13419547

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.