Evidence map›Paper›PMID 42534168›Full record

ArticleCritical public health2026

A turning point for youth HIV care in the United States: tailored strategies for adolescents and young adults.

Omar Martinez, Maria Trent, Sybil Hosek, Jose Bauermeister, Julio Nazario-Valle, Rahim Miller, Larissa Jennings Mayo-Wilson, Zoë Njemanze, Jim Pickett, Michelle Ogle and 7 more

Abstract read
In one paragraph

Article in Critical public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Omar MartinezCollege of Medicine, University of Central Florida, Orlando, FL, USA.
Maria TrentJohn Hopkins Bloomberg School of Public Health, John Hopkins University, Baltimore, MD, USA.
Sybil HosekCollege of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Jose BauermeisterSchool of Nursing, University of Pennsylvania, Philadelphia, PA, USA.
Julio Nazario-ValleVolusia County Schools, DeLand, FL, USA.
Rahim MillerSchool of Nursing, Florida State University, Tallahassee, FL, USA.
Larissa Jennings Mayo-WilsonGillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Zoë NjemanzeSchool of Nursing, Florida State University, Tallahassee, FL, USA.
Jim PickettJim Pickett, Chicago, IL, USA.
Michelle OgleDepartment of Pediatrics, Albert Einstein College of Medicine, New York, NY, USA.
Abigail EnglishAbigail English, Chapel Hill, NC, USA.
Adrian WilliamsSchool of Nursing, Florida State University, Tallahassee, FL, USA.
Judah DeanSchool of Nursing, Florida State University, Tallahassee, FL, USA.
Patricia EmmanuelCollege of Medicine, University of South Florida, Tampa, FL, USA.
Tina SimpsonSchool of Medicine, Tulane University, New Orleans, LA, USA.
Kristina ClaudeSchool of Nursing, Florida State University, Tallahassee, FL, USA.
Lisa Hightow-WeidmanSchool of Nursing, Florida State University, Tallahassee, FL, USA.

Funding

SDMC; Statistical Data Mgmt CoreUM2HD111102 · NICHD · FLORIDA STATE UNIVERSITY · PI Lisa B Hightow-Weidman, Sybil Hosek · 2023 to 2026
$49.7M
University of South Florida Site Consortium - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)UM2HD111076 · NICHD · WESTAT, INC. · PI Karen Megazzini, Daniel Hunter Reirden · 2022 to 2026
$47.7M
NICHD NIH HHS UM2 HD111076NICHD NIH HHS UM2 HD111102
6 · The paper itself

Abstract

Adolescents and young adults (AYAs; ages 13-24) remain an underserved and disproportionately affected population within the United States (U.S.). HIV epidemic. Despite overall national declines in HIV incidence, youth continue to account for approximately one in five new infections, with persistent disparities among Black and Latino youth, other structurally vulnerable youth, and those living in the Southern U.S. These inequities reflect structural barriers and developmental mismatches between youth needs and adult-oriented HIV prevention and care systems. This commentary examines the evolving landscape of HIV among AYAs, highlighting persistent gaps in testing, linkage, retention, and viral suppression. Drawing on national surveillance data and a case example from Orange County, Florida, we illustrate how developmental vulnerability, stigma, and fragmented systems undermine engagement across the HIV care continuum. We highlight emerging opportunities, including long-acting injectable antiretroviral therapy and PrEP, digital health tools, and youth-focused case management, and emphasize the role of implementation science frameworks in adapting and sustaining these innovations. We argue that meaningful progress will require embedding youth voices in program design, addressing structural determinants of health through legal aid, and committing to sustained investment in youth-centered strategies. Reimagining the HIV response with adolescents and young adults at the center is essential to achieving progress toward national and global HIV targets.

Indexed as

Adolescents and young adultsending the HIV epidemicHIV continuum of careimplementation scienceyouth HIV prevention

Identifiers

PMID42534168
PMCPMC13419682

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.