Evidence map›Paper›PMID 42535042›Full record

ReviewCureus2026

Fecal Microbiota Transplantation (FMT) in the Management of Ulcerative Colitis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials (RCTs).

Amal Ahad, Sandeep Kumar, Hugh Kolomar, Jada Williams, Abrar I Abdallah, Amirali Sadeghzadegan, Dana Yateem, Punam Kharel, Dristy Chowdhury, Fahad Alnajar and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amal AhadDepartment of Endocrinology, Pinderfields Hospital, Wakefield, GBR.
Sandeep KumarDepartment of Medicine, Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, GBR.
Hugh KolomarDepartment of Medicine, Niš Clinical Centre, Nis, SRB.
Jada WilliamsDepartment of Medicine, St. George's University, Brooklyn, USA.
Abrar I AbdallahDepartment of Surgery, Sulaiman Alhabib Hospital, Jeddah, SAU.
Amirali SadeghzadeganDepartment of Medicine, Marmara University School of Medicine, Istanbul, TUR.
Dana YateemDepartment of Trauma and Orthopaedics, The Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, GBR.
Punam KharelDepartment of Respiratory Medicine, Medway NHS Foundation Trust, Gillingham, GBR.
Dristy ChowdhuryDepartment of Hematology and Oncology, Medway NHS Foundation Trust, Gillingham, GBR.
Fahad AlnajarDepartment of Medical Education, Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Dubai, ARE.
Muqaddas AliDepartment of Medicine, Medipol University, Beykoz, TUR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon with increasing global prevalence, particularly in newly industrialized countries. Fecal microbiota transplantation (FMT) has worked as an effective therapeutic strategy aimed at restoring immune homeostasis and gut microbial balance. However, a lack of standardized protocols and comprehensive safety data necessitates further evaluation. This meta-analysis aims to comprehensively analyze the efficacy of FMT in inducing clinical remission in UC, incorporating the latest randomized controlled trials (RCTs). A systematic review and meta-analysis of RCTs investigating FMT in UC were conducted. The primary outcomes were clinical and endoscopic remission, while adverse events (AEs) were assessed as secondary outcomes. Pooled risk ratios (RRs) with 95% confidence intervals (CIs) were calculated, and heterogeneity was analyzed using the I

Indexed as

clinical remissionendoscopic remissionfecal microbiota transplantationmeta-analysisulcerative colitis

Identifiers

PMID42535042
PMCPMC13423146

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.