Evidence mapPaperPMID 42536549Full record

Trial reportMedicine2026

Application of gastric tube removal strategy based on the combination of Gugging Swallowing Screen (GUSS) and National Institutes of Health Stroke Scale (NIHSS) scores in patients following acute stroke: A randomized controlled trial.

Xiapei Peng, Na Li, Fang Zeng, Meng Zhang, Yang Liu, Li Zhang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiapei PengDepartment of Neurology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Na Li
Fang Zeng
Meng Zhang
Yang Liu

Funding

Wuhan Health Commission WX21D14
6 · The paper itself

Abstract

backgroundDysphagia is a common, serious complication in acute stroke patients, often requiring indwelling gastric tubes. Prolonged tube use increases risks of aspiration pneumonia and other adverse events. Current assessment methods often lack the sensitivity needed to guide safe extubation. To investigate the effect of combined Gugging Swallowing Screen (GUSS) and National Institutes of Health Stroke Scale (NIHSS) scores on the gastric tube removal in acute stroke patients.

methodsBetween November 2021 and November 2022, 110 patients were admitted to our hospital with acute stroke and fitted with an indwelling gastric tube. We collated clinical data, performed the Kubota Water Swallowing Test, and determined the NIHSS and GUSS scores. Patients were then divided randomly into experimental and control groups. In the experimental group, gastric tubes were removed based on an NIHSS score < 15 and a GUSS score ≥ 15, while in the control group, extubation followed the Kubota Water Swallowing Test. Adverse events related to the 2 strategies were analyzed.

resultsNo significant differences were detected between the 2 groups in terms of baseline clinical characteristics. When compared to the traditional extubation strategy based on the Kubota Water Swallowing Test, the incidence of aspiration pneumonia, indwelling time for the gastric tube, and the secondary indwelling rate associated with the combination of GUSS and NIHSS scores were significantly (P < .05) reduced. Cox and Kaplan-Meier curves demonstrated that the extubation strategy applied in the experimental group significantly (P < .05) reduced the risk of adverse events.

conclusionAn NIHSS score < 15 and a GUSS score ≥ 15 can be used to approve the removal of a gastric tube from acute stroke patients; this represents a reliable and safe strategy that reduces the risk of adverse events.

Indexed as

Deglutition DisordersDevice RemovalIntubation, GastrointestinalStrokeAgedAged, 80 and overDeglutitionFemaleHumansMaleMiddle AgedPneumonia, AspirationUnited Statesacute strokegastric tube extubation strategyGugging Swallowing Screen (GUSS)Kaplan–Meier (KM)Kubota Water Swallowing TestNational Institutes of Health Stroke Scale (NIHSS)

Identifiers

PMID42536549
PMCPMC13433064

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.