Evidence map›Paper›PMID 42538140›Full record

ArticleJournal of the peripheral nervous system : JPNS2026

Neurophysiological Characteristics of Nitrous Oxide-Induced Polyneuropathy: A Case Series.

Tanya Elisabeth Bentley, Volker Limmroth, Maximilian Zimmermann, Johannes Fabian Holle

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Article in Journal of the peripheral nervous system : JPNS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tanya Elisabeth BentleyDepartment of Neurology, Hospitals of the City of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-8835-9223
Volker LimmrothDepartment of Neurology, Hospitals of the City of Cologne, Cologne, Germany.
Maximilian ZimmermannHealth Faculty/Department for Human Medicine, University of Witten/Herdecke, Witten, Germany.
Johannes Fabian HolleDepartment of Neurology, Hospitals of the City of Cologne, Cologne, Germany.ORCID https://orcid.org/0009-0002-2140-906X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNitrous oxide (N

methodsWe reviewed the records of 12 patients with acute neurological symptoms and a history of N

resultsConduction studies revealed evidence of PNP in eight out of 12 patients and the most common pattern was pure motor (5/8). No distinct clinical phenotype could be identified for patients with electrophysiologically confirmed PNP or Pure-Motor PNP. SSEPs were abnormal in all assessable patients, whereas signs of SCD on MRI were present in a smaller proportion. Only three of 10 tested patients had reduced vitamin B12 levels, while all showed elevated methylmalonic acid (MMA) levels. Mean MMA levels were higher in patients with PNP than in those without.

interpretationThe reason why N

Indexed as

Nitrous OxidePolyneuropathiesAdultEvoked Potentials, SomatosensoryFemaleHumansMaleMethylmalonic AcidMiddle AgedNerve Conduction StudiesRetrospective StudiesMethylmalonic AcidNitrous Oxideelectrodiagnostic studiesmethylmalonic acidnitrous oxidepolyneuropathyvitamin B12

Identifiers

PMID42538140
PMCPMC13427618

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.