Evidence map›Paper›PMID 42538425›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2026

Protective effects of ginseng against reproductive injury: mechanisms and research progress.

Chao Jiang, Wei Li, Ying-Ping Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chao JiangCollege of Chinese Medicinal Materials, Jilin Provincial International Joint Research Center for the Development and Utilization of Authentic Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China.
Wei LiCollege of Chinese Medicinal Materials, Jilin Provincial International Joint Research Center for the Development and Utilization of Authentic Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China. liwei7727@126.com.
Ying-Ping WangCollege of Chinese Medicinal Materials, Jilin Provincial International Joint Research Center for the Development and Utilization of Authentic Medicinal Materials, Jilin Agricultural University, Changchun, 130118, China. ypwang@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reproductive injury is a core pathological process leading to gamete dysfunction, gonadal structural damage, and impaired reproductive capacity. Basic research has revealed that its pathogenesis involves a complex regulatory network of oxidative stress, inflammatory response, germ cell apoptosis, hypothalamic-pituitary-gonadal (HPG) axis disorder, mitochondrial dysfunction, and epigenetic dysregulation. Panax ginseng C. A. Meyer, a classic medicinal and edible herb, and its bioactive constituents have shown reproductive protective effects in numerous in vitro and in vivo basic studies. This review systematically summarizes the core pathological mechanisms of reproductive injury revealed by basic research, sorts out the main bioactive constituents of ginseng and their remarkable functional characteristics in reproductive protection, focuses on the potent molecular mechanisms and basic research progress of ginseng and its active ingredients against reproductive injury, and identifies the limitations of current basic research and future research directions. This review aims to provide a systematic theoretical basis for further basic research of ginseng in the field of reproductive protection, and to support the in-depth exploration of its intervention mechanism and active ingredient development.

Indexed as

GinsengGinsenosideOvarian agingReproductive injurySpermatogenesis

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.