ArticleFrontiers in cardiovascular medicine2026
Association of the sdLDL-C/lbLDL-C ratio with heart failure beyond conventional LDL-C levels: a cross-sectional study.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Heart failure (HF) is one of the major cardiovascular diseases and the leading cause of death globally. Blood lipid profile is associated with HF early risk. Therefore, we aimed to explore the association between blood lipid profile and HF. Methods: A total of 584 newly diagnosed HF patients and 611 non-HF controls were included. Clinical characteristics and routine lipid parameters were collected. LDL-C subfractions (LDLC-1 to LDLC-7) were quantified using the LDL subfractions kit. Multivariable logistic regression analysis was performed to identify independent correlates of HF. Results: Among 584 HF patients and 611 controls, conventional LDL-C did not significantly differ between groups. However, HF patients had significantly higher sdLDL-C level, lower lbLDL-C level, and higher sdLDL-C/lbLDL-C ratio than controls. Multivariable logistic regression identified sdLDL-C/lbLDL-C ratio (OR = 2.199, 95%CI: 1.293-3.874, Conclusions: Lipoprotein subfraction characteristics, particularly the sdLDL-C/lbLDL-C ratio, is significantly associated with HF status and cardiac function.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.