Evidence map›Paper›PMID 42539665›Full record

ReviewFundamental research2026

Artificial intelligence for design strategies of tissue engineering materials.

Mingru Kong, Yuting Zeng, Zhen Wu, Hao Deng, Binrui Zhang, Dongyi Feng, Yuxiang Zhang, Wenjun Zhang, Xiaodong Fu, Leyu Wang

Abstract readReview
In one paragraph

Review in Fundamental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Advancements in Functional Polymeric Scaffolds for Scar-Free Skin Regeneration.Polymer science & technology (Washington, D.C.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mingru KongDepartment of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 510120, China.
Yuting ZengDepartment of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 510120, China.
Zhen WuDepartment of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 510120, China.
Hao DengNanshan School of Guangzhou Medical University, Guangzhou 510120, China.
Binrui ZhangGuangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, Biomaterials Research Center, School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
Dongyi FengDepartment of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 510120, China.
Yuxiang ZhangDepartment of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 510120, China.
Wenjun ZhangDepartment of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 510120, China.
Xiaodong FuDepartment of Cardiology, Guangzhou Institute of Cardiovascular Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China.
Leyu WangDepartment of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 510120, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, artificial intelligence (AI), driven by machine learning (ML) and deep learning (DL) algorithms, has fundamentally transformed the design and performance prediction of tissue engineering materials. By analyzing large amounts of biomaterial data, ML has demonstrated remarkable effectiveness in optimizing mechanical properties, assessing biocompatibility, and enhancing the structural design of tissue engineering materials, while also accurately predicting the complex interactions between materials and cells. Due to its exceptional ability to process nonlinear data, DL is particularly effective in analyzing complex biological data, such as interactions between tissue engineering materials, cells, and proteins, as well as promoting tissue regeneration. This review systematically examines ML- and DL-based design methods for tissue engineering materials and their important applications in recent years. It also explores their technical advantages, challenges, and future directions, providing insights for advancing regenerative medicine.

Indexed as

Artificial intelligenceDeep learningDesign of biomaterialsMachine learningTissue engineering

Identifiers

PMID42539665
PMCPMC13424160

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.