Evidence mapPaperPMID 42540283Full record

ArticleACS omega2026

Molybdenum Nanoparticles Alleviate Psoriasis-Related Cardiovascular Oxidative Stress and Inflammation.

Jing Guo, Qin Xiao, Jin Gao, Chuanlong Jia, Yongzhou Lu, Chengchen Gong, Yijie Cai, Qiannan Xu, Nan Xu

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jing GuoDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Qin XiaoDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Jin GaoDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Chuanlong JiaDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Yongzhou LuDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Chengchen GongDepartment of Dermatology, Changzheng Hospital, 200003 Shanghai, China.
Yijie CaiDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Qiannan XuDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Nan XuDepartment of Dermatology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.ORCID https://orcid.org/0009-0008-3350-0243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a common immune-mediated chronic inflammatory disease, and its impact on patients extends beyond the skin. With the continuous deepening of understanding of psoriasis, the multisystem comorbidities of psoriasis have gradually been revealed. These comorbidities include cardiovascular diseases, metabolic diseases, liver and kidney diseases, autoimmune diseases, digestive system diseases, and mental disorders, etc. Among them, the cardiovascular comorbidities of psoriasis, as they can lead to fatal myocardial infarction and affect the survival rate of patients, deserve attention. Based on previous studies, this research further explores the effect of a molybdenum nanoparticle suspension (MNS) on psoriasis-related cardiovascular inflammation. The study found that the content of ROS in the cardiovascular tissues of psoriasis model mice, the infiltration of inflammatory cells, and the expression of inflammatory mediators (TNF-α, IFN-γ, IL-1β, IL-6, and IL-17) were significantly increased, and decreased after treatment with MNS. In addition, cardiomyocyte hypertrophy observed in the model group was alleviated following MNS intervention, and the ROS/NF-κB axis may be associated with psoriasis-related cardiovascular oxidative stress and inflammation.

Identifiers

PMID42540283
PMCPMC13425494

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.