Evidence map›Paper›PMID 42543254›Full record

ArticleDiabetes, obesity & metabolism2026

Socioeconomic and Linguistic Factors in Paediatric Type 1 Diabetes: Exploring Glycemic Outcomes, Technology Use, and Residual Beta-Cell Function in Migrant-Background Populations.

Silvia Savastio, Andrea E Scaramuzza, Erica Pozzi, Valeria Castorani, Eleonora Chiarle, Aurora Craici, Valentina Todescato, Claudio Cavalli, Ivana Rabbone

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Article in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Silvia SavastioDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Andrea E ScaramuzzaPediatric Diabetes, Endocrinology and Nutrition, Pediatric Unit, ASST Cremona, Ospedale Maggiore, Cremona, Italy.ORCID 0000-0002-1518-8515
Erica PozziDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Valeria CastoraniDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.ORCID 0000-0001-5024-0545
Eleonora ChiarleDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Aurora CraiciDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
Valentina TodescatoPediatric Diabetes, Endocrinology and Nutrition, Pediatric Unit, ASST Cremona, Ospedale Maggiore, Cremona, Italy.
Claudio CavalliPediatric Diabetes, Endocrinology and Nutrition, Pediatric Unit, ASST Cremona, Ospedale Maggiore, Cremona, Italy.
Ivana RabboneDivision of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.ORCID 0000-0003-4173-146X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate associations between migrant status, socioeconomic factors (SES), and residual beta-cell function and glycemic outcomes in paediatric type 1 diabetes.

methodsRetrospective study of 208 children (median [IQR] age 11 [8-14] years; 119 Italian, 89 from migrant-background families) with glucometric (HbA1c, TIR, TITR, TAR, CV), SES (maternal/paternal education, language, income), and metabolic data. Univariable and exploratory multivariable regression analyses identified factors associated with glycemic control.

resultsChildren from migrant-background families presented with more severe metabolic crisis at onset (pH 7.28 vs. 7.35, p = 0.047; C-peptide 0.24 vs. 0.32 ng/mL, p = 0.010). Despite higher AID usage (80.6% vs. 68.1%), children from migrant-background families showed significantly worse glycemic control: higher HbA1c (7.8% vs. 7.0%, p < 0.001), lower TIR (57% vs. 65%, p = 0.004), and greater glycemic variability (CV 39.3% vs. 35.0%, p < 0.001). Socioeconomic disparities were marked, with 63.4% of migrant mothers unemployed (vs 16.6%, p < 0.001). In multivariable analysis, migrant status was associated with higher HbA1c (β +0.70, p < 0.001), while AID use (β +10, p < 0.001) and high maternal education (β +7.86, p = 0.004) were associated with higher TIR.

conclusionsIn this retrospective cohort, children and adolescents from migrant-background families had poorer glycemic outcomes despite high AID uptake and comparable C-peptide levels at follow-up. Technology provision alone may be insufficient to eliminate socioeconomic and linguistic disparities in glycemic control, and interventions targeting education, language support, and family-level self-management capacity may be beneficial.

Indexed as

Diabetes Mellitus, Type 1Insulin-Secreting CellsTransients and MigrantsAdolescentBlood GlucoseBlood Glucose Self-MonitoringChildFemaleGlycated HemoglobinGlycemic ControlHumansInsulin Infusion SystemsItalyMaleRetrospective StudiesSocioeconomic Disparities in HealthBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanadolescentsautomated insulin delivery systemschildrencoefficient of variationC‐peptideglycated haemoglobinmigrant healthsocioeconomic factorstime in range

Identifiers

PMID42543254
PMCPMC13538815

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.