Evidence map›Paper›PMID 42545114›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels.

Nozie D Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nozie D AghaizuInstitute for Biology, Experimental Biophysics/Mechanobiology, Humboldt Universität Zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-6096-1853
Willi WeberInstitute for Biology, Experimental Biophysics/Mechanobiology, Humboldt Universität Zu Berlin, Berlin, Germany.
Nadine StrempelCharité Universitätsmedizin, Berlin, Germany.ORCID https://orcid.org/0009-0001-2207-177X
Asya PolatInstitute for Biology, Experimental Biophysics/Mechanobiology, Humboldt Universität Zu Berlin, Berlin, Germany.ORCID https://orcid.org/0009-0008-9503-3177
Enrico KlotzschInstitute for Biology, Experimental Biophysics/Mechanobiology, Humboldt Universität Zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-7577-9042

Funding

Deutsche Forschungsgemeinschaft 3278/2-1
6 · The paper itself

Abstract

B cell activation typically involves binding of presented antigen by the B cell receptor. Ensuing intracellular signaling with Ca

Indexed as

B cellbiologycell biologyintracellularion channelmechanosensitive channelsnanomaterialspharmacology

Identifiers

PMID42545114
PMCPMC13430938

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.