Evidence map›Paper›PMID 42548427›Full record

ArticleCHEST pulmonary2026

Association of Health Literacy With Survival in Patients With Lung Cancer.

Patrick Meyers, Palina Woodhouse, Emma Bradley, Stephen Deppen, Aimal Khan, Eric S Lambright, Sunil Kripalani, Kamran Idrees, Eric L Grogan

Abstract read
In one paragraph

Article in CHEST pulmonary, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patrick MeyersVeterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville Campus, Vanderbilt University Medical Center, Nashville, TN.
Palina WoodhouseVeterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville Campus, Vanderbilt University Medical Center, Nashville, TN.
Emma BradleyDepartment of Surgery, Division of Surgical Oncology, Vanderbilt University Medical Center, Nashville, TN.
Stephen DeppenVeterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville Campus, Vanderbilt University Medical Center, Nashville, TN.
Aimal KhanDepartment of Surgery, Division of Surgical Oncology, Vanderbilt University Medical Center, Nashville, TN.
Eric S LambrightVeterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville Campus, Vanderbilt University Medical Center, Nashville, TN.
Sunil KripalaniDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Kamran IdreesDepartment of Surgery, Division of Surgical Oncology, Vanderbilt University Medical Center, Nashville, TN.
Eric L GroganVeterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville Campus, Vanderbilt University Medical Center, Nashville, TN.

Funding

Validation of Biomarkers of Risk for the Early Detection of Lung CancerU01CA152662 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DEPPEN, STEPHEN, GROGAN, ERIC L · 2010 to 2025
$12.8M
NCI NIH HHS U01 CA152662
6 · The paper itself

Abstract

Background: Lung cancer is the leading cause of cancer-related deaths globally, with survival influenced by stage at diagnosis, comorbidities, and sociodemographic factors. Health literacy, which impacts patients' understanding of medical information and decision-making, has not been well studied in lung cancer survival outcomes. Research Question: In a retrospective cohort of patients diagnosed with lung cancer, how is health literacy associated with overall survival and cancer stage at diagnosis? Study Design and Methods: This retrospective cohort study included patients diagnosed with lung cancer between 2010 and 2022 at a single institution. Health literacy was measured using the Brief Health Literacy Screen (BHLS). Patients were divided into low health literacy (BHLS score ≤ 9) and intermediate-high health literacy (BHLS score > 9) groups. Data on demographics, clinical characteristics, and treatment were collected. Logistic regression examined associations between health literacy and patient characteristics. Cox proportional hazard models evaluated the impact of health literacy on survival, adjusting for covariates. Results: The study included 3,828 patients with lung cancer, and 19.1% (n = 730) had low health literacy. Logistic regression indicated that older age, male sex, non-White race/ethnicity, and lower education were associated with low health literacy. Stage IV disease was associated with increased odds of low health literacy by 65% compared with stage I disease (OR, 1.65; Interpretation: Our results show that low health literacy is associated with late-stage diagnosis and reduced overall survival in patients with lung cancer. Interventions addressing limited health literacy for patients with lung cancer could alleviate these disparities.

Indexed as

cancer stagehealth literacylung canceroverall survivalsocial determinants of health

Identifiers

PMID42548427
PMCPMC13419145

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.