Evidence map›Paper›PMID 42548694›Full record

ArticleFrontiers in pharmacology2026

Timosaponin AIII inhibits gastric cancer growth by the promotion of programmed cell death via the activation of p300/acetyl-p53 and Akt/MEK/ERK signaling.

Kaizhen Tang, Wairong Zhao, Jing Zhang, Guangyu Wang, Wenting Shi, Meiyan Yue, Yan Lin, Yanli Fu, Zhongyan Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaizhen Tang *Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wairong Zhao *Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jing Zhang *Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Guangyu WangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wenting ShiLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Meiyan YueLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yan LinDepartment of Oncology, The Fourth Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Yanli FuDepartment of Oncology, Shenzhen (Fu Tian) Hospital, Guangzhou University of Chinese Medicine, Guangdong, China.
Zhongyan ZhouLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is a common cancer and causes severe deaths worldwide, while the current treatment cannot meet its medical needs. Timosaponin AIII (Timo AIII) is an active component isolated from

Indexed as

gastric cancerp300p53programmed cell deathtimosaponin AIIIzebrafish

Identifiers

PMID42548694
PMCPMC13429718

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.