Evidence mapPaperPMID 42548706Full record

ReviewFrontiers in immunology2026

Reader-dependent functional duality of FTO: a context-switching node at the intersection of immune evasion and therapeutic resistance.

WenJie Tian, Bin Xie, Peng Zhan

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

WenJie TianDepartment of Urology, the Second Hospital of Jilin University, Changchun, China.
Bin XieDepartment of Biliary Surgery, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital& Institute, Shenyang, Liaonin, China.
Peng ZhanDepartment of Urology, the Second Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fat mass and obesity-associated protein (FTO), an RNA demethylase acting on both internal m

Indexed as

Alpha-Ketoglutarate-Dependent Dioxygenase FTODrug Resistance, NeoplasmNeoplasmsTumor EscapeAnimalsEpitranscriptomeEpitranscriptomicsHumansMetabolic ReprogrammingAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanFTOimmune checkpoint regulationmetabolic reprogrammingtherapeutic resistancetumor immune microenvironment

Identifiers

PMID42548706
PMCPMC13429790

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.